Thursday, February 14, 2013

Why neurobiologists make the best lovers.




In the spirit of Saint Valentine's day, I decided to look into the neurobiological origins of feelings. The neural substrates for feelings can be found at all levels of the nervous system, from individual neurons to subcortical nuclei and cortical regions. Since neurobiologists have insight into the brain, and the brain is responsible for feelings, that should make us all good lovers ... right?

The prime candidates for the neural substrates of feelings are regions concerned with interoception, which is the sense that continuously monitors the internal milieu and provides the CNS with real-time information on the state of the body. If one considers the main contributors to interoception, in terms of the traditional Valentine's day gifts and activities, it becomes clear why they are tried and true. The main contributors to interoception are chemosensation (the lovely smell of roses), thermo-algic sensation for temperature (romantic dip in a hot tub) and pain perception (I will leave that one to your imagination) and visceral sensation (the fullness of a gut after fancy dinner or eating chocolates). Okay, maybe that's a little simplistic. But if you want to read more I recommend checking out the following recent review: 

Nature Reviews Neuroscience 14, 143-152 (February 2013) | doi:10.1038/nrn3403

OPINION:The nature of feelings: evolutionary and neurobiological origins

Antonio Damasio & Gil B. Carvalho

Monday, February 11, 2013

Science: It's a nerd thing.


We have all heard of ‘the leaky pipeline’. This issue of retaining women in top positions is often attributed to child rearing responsibilities. Although not the only factor, it is the most discussed  and after at least three decades into this debate, it seems we are still not much closer to solution.  So what else are we doing?


Recently I have been inspired by forums for advocacy of women in science that try to attack the problem by promoting gender neutral actions and discussions. One of my current favorites includes ScienceGrrl (http://www.sciencegrrl.co.uk/) – a group that started in response to insipid and tragically sexist attempts at attracting girls to science like this:






Simply put, science is for everyone. We don't need to perpetuate stereotypes to get someone to consider a career in science. 

Friday, February 8, 2013

The Art of Science


Look on any academic or biomedical website, and you will see researchers in the midst of ‘performing’ an experiment: Usually pipeting some ubiquitous pink liquid, wearing a crisp white lab coat and safety glasses. These images are used to reinforce the stereotypical view of scientists as calculating, logical, and knowledgeable. Many would be surprised about the creativity commonly found among people in the laboratory. Throughout my career in biomedical research, I have met many scientists whom were also talented musicians, painters, and photographers. I myself, dabbled with the idea of a degree in fine arts, before making the ‘sensible’ decision to enter neuroscience. This link between the creative and empirical is not merely a rejuvenation of the renaissance and Leonardo Di Vinci. The marriage of art and science persists – not because they are complementary components in our culture – but because they tap into the same creative process for their success.

Not surprisingly, that part of our collective unconscious according to Jungian psychology, is the Artist-Scientist archetype: “They are a builder, an inventor, a seeker, a dreamer, and a thinker. Distracted by their own thoughts, they frequently have to be pulled in out of the rain. They are simultaneously vastly knowledgeable and yet innocent, impulsive yet cautious.” This description not only accurately describes every professor I have worked for, but as my friends can attest, is also a good fit for me too.

If art and creativity inspires and complements the efforts of scientists, what about the inverse relationship? Does science inspire art? Custom DNA portraits allows one to “frame your inner beauty”, producing a print to hang on your wall that is as unique as you. Although this example is rather pedestrian, it does exemplify how art is a medium to explore current culture – in this case, it is the culture of genomic research. In more academic circles, the medical research charity the Wellcome Trust in the UK, and STAGE (Scientists, Technologists and Artists Generating Exploration) in the US, actively engages artists and scientists to work together through the funding of collaboration. These projects involve the creation of new artistic work that has biomedical scientific input into the process, either through a scientist taking on an advisory role or through direct collaboration. This has lead to many dynamic and unique working relationships between poets and speech pathologists, composers and rheumatologists, documentary film directors and psychologists.

Some neuroscientists suggest that the fundamental creative urge and key skills of pre- verbal (i.e. creative) thinking are the same regardless of the mode of expression: artistic or scientific. Patterns of activation during an fMR word association task performed by artists and scientists show strikingly similar patterns of activation in multiple regions of association cortex and areas involved in socio-affective processing. Science educators should take note. We are forever lamenting the lack of students, particularly female, entering into fields of math and science. Fostering appreciation and love of art and the creative process, as something that is a part of science -- rather than apart from it, as in the current education system -- could hold the key to this dilemma. Albert Einstein one said, "The greatest scientists are artists as well". But maybe Einstein was just being biased: He was just a musician after all.

Insane in the Chromatophores


It's a movie that has been out for awhile, but it puts a smile on my face every time.

Turn up the volume, and enjoy!



Nerdoscientist - Origins

Hello world. Welcome to Nerdoscientist, the blog about neuroscience with a nerdy edge. 

I am a nerdoscientist. In more contemporary circles I am referred to as a neuroscientist. As a first post, I thought I should explain the origins of this word, it's meaning, and how to observe and interact with nerdoscientists in their natural habitat.

It was my husband who first coined the word nerdoscientist when he was asked by a friend to explain what it is I do at my work. He felt it accurately described in just one word the "biological, brainy, nerdy, experimenty things" that I did all day, "and oh yeah, there are lasers somewhere in there too." He wasn't being dismissive about what I did for living by making it into a joke. I think he was just tired of trying to understand all those papers I would read, and why I was very upset when my neurons died, etc. To be honest and in his defense, I have no idea about what my husband does either.

Almost instantaneously, it started to become part of our vernacular  Some days I was "in full nerdoscientist mode". Or when there was a party my husband would ask, "Is it just a nerdoscientist thing, or will there be other people?"

As a formal definition, nerdoscientist is a noun, referring to a person of the neuro-scientific community who is passionate about their work. The technical and state-of-the-art aspects of neuroscience inspires and excites them. They are often found in the lab, not only performing experiments, but also hunched over a piece of equipment that has been dismantled in an effort to 'improve it'. On rare occasions, the nerdoscientist may migrate to a party or  pub. Generally genial company and adept at great conversation, they enjoy partaking in alcoholic beverages. But be warned, in the presence of more than one nerdoscientist, these evenings almost inevitably will involve 'talking shop'. 

This blog is for all the nerdoscientists out there. It is a forum for discussing issues that effect us, and celebrate the achievements of fellow nerdoscientists -- always with a healthy dose of humor, and inevitably, with a nerdy edge.